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Senior Contributing Member
Posts: 3,497

Only one new drug has become available over the past 50 years for the estimated 1.5 million Americans and five million-plus people worldwide suffering from lupus, but new research has identified a previously unknown mechanism involved in the immune response that could provide an alternative therapy target.

Lupus (also known as systemic lupus erythematosus) is a chronic autoimmune disease in which the immune system is unable to distinguish the difference between foreign invaders, such as viruses and bacteria, from its own healthy body tissue, so it attacks itself, damaging skin, joints, and kidneys - among other organs - in the process. The disease is also marked by elevated levels of type I interferon, a substance normally secreted by immune cells in response to viral infections. The origin of the interferon signature in lupus has remained a mystery for years.

When the first baby laughed for the first time, its laugh broke into a thousand pieces, and they all went skipping about, and that was the beginning of fairies. 

Junior Member
Posts: 22
Thanks for posting! It's so sad that in fifty years only one medication made for lupus? It amazes me the puzzled looks that the medical staff gives me when I say that I have lupus? It scares me to think that I could end up in a local hospital unable to tell them to send me to my out of state rheumatologist! Sad

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Active Member
Posts: 39

Thanks Robin

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Life is what happens while we are planning to do something else.
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